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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50041259
Substrate
n/a
Meas. Tech.
ChEBML_201915
Ki
0.170000±n/a nM
Citation
 Glennon, RA; Ismaiel, AM; Ablordeppey, S; El-Ashmawy, M; Fisher, JB Thioxanthene-derived analogs as sigma(1) receptor ligands. Bioorg Med Chem Lett 14:2217-20 (2004) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25124.85
Organism:
Homo sapiens (Human)
Description:
Q99720
Residue:
223
Sequence:
MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50041259
Synonyms:
CHEMBL19355 | Phenethyl-(5-phenyl-pentyl)-amine
Type:
Small organic molecule
Emp. Form.:
C19H25N
Mol. Mass.:
267.4085
SMILES:
C(CCNCCc1ccccc1)CCc1ccccc1
Structure:
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