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Target
5-hydroxytryptamine receptor 2A
Ligand
BDBM50001915
Substrate
n/a
Meas. Tech.
ChEMBL_2292 (CHEMBL617077)
Ki
54±n/a nM
Citation
 Bentley, JM; Adams, DR; Bebbington, D; Benwell, KR; Bickerdike, MJ; Davidson, JE; Dawson, CE; Dourish, CT; Duncton, MA; Gaur, S; George, AR; Giles, PR; Hamlyn, RJ; Kennett, GA; Knight, AR; Malcolm, CS; Mansell, HL; Misra, A; Monck, NJ; Pratt, RM; Quirk, K; Roffey, JR; Vickers, SP; Cliffe, IA Indoline derivatives as 5-HT(2C) receptor agonists. Bioorg Med Chem Lett 14:2367-70 (2004) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 2A
Synonyms:
5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A
Type:
undefined
Mol. Mass.:
52607.65
Organism:
Homo sapiens (Human)
Description:
P28223
Residue:
471
Sequence:
MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
  
Inhibitor
Name:
BDBM50001915
Synonyms:
1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlorophenylpiperazine | mCPP
Type:
Small organic molecule
Emp. Form.:
C10H13ClN2
Mol. Mass.:
196.677
SMILES:
Clc1cccc(c1)N1CCNCC1
Structure:
Search PDB for entries with ligand similarity: