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Target
D(2) dopamine receptor
Ligand
BDBM50145028
Substrate
n/a
Meas. Tech.
ChEMBL_62877 (CHEMBL673588)
Ki
3670±n/a nM
Citation
 Berardi, F; Ferorelli, S; Abate, C; Colabufo, NA; Contino, M; Perrone, R; Tortorella, V 4-(tetralin-1-yl)- and 4-(naphthalen-1-yl)alkyl derivatives of 1-cyclohexylpiperazine as sigma receptor ligands with agonist sigma2 activity. J Med Chem 47:2308-17 (2004) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50145028
Synonyms:
1-Cyclohexyl-4-[4-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-butyl]-piperazine | 1-cyclohexyl-4-(4-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)butyl)piperazine | CHEMBL77220
Type:
Small organic molecule
Emp. Form.:
C25H40N2O
Mol. Mass.:
384.5979
SMILES:
COc1cccc2C(CCCCN3CCN(CC3)C3CCCCC3)CCCc12
Structure:
Search PDB for entries with ligand similarity: