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Target
D(2) dopamine receptor
Ligand
BDBM50151957
Substrate
n/a
Meas. Tech.
ChEBML_305865
IC50
>100±n/a nM
Citation
 Heinrich, T; Böttcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Indolebutylamines as selective 5-HT(1A) agonists. J Med Chem 47:4677-83 (2004) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50151957
Synonyms:
3-[4-(4-Benzo[1,3]dioxol-5-yl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-5-methoxy-1H-indole | CHEMBL186814
Type:
Small organic molecule
Emp. Form.:
C25H28N2O3
Mol. Mass.:
404.5014
SMILES:
COc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccc4OCOc4c3)c2c1 |c:16|
Structure:
Search PDB for entries with ligand similarity: