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Target
Tubulin beta-2B chain
Ligand
BDBM50159568
Substrate
n/a
Meas. Tech.
ChEMBL_312291 (CHEMBL837869)
IC50
2000±n/a nM
Citation
 Maya, AB; Pérez-Melero, C; Mateo, C; Alonso, D; Fernández, JL; Gajate, C; Mollinedo, F; Peláez, R; Caballero, E; Medarde, M Further naphthylcombretastatins. An investigation on the role of the naphthalene moiety. J Med Chem 48:556-68 (2005) [PubMed]  Article 
Target
Name:
Tubulin beta-2B chain
Synonyms:
TBB2B_BOVIN | TUBB2B | Tubulin | Tubulin beta chain
Type:
PROTEIN
Mol. Mass.:
49932.38
Organism:
Bos taurus
Description:
ChEMBL_211651
Residue:
445
Sequence:
MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEEGEDEA
  
Inhibitor
Name:
BDBM50159568
Synonyms:
1-Methyl-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-1H-indole | CHEMBL175504
Type:
Small organic molecule
Emp. Form.:
C20H21NO3
Mol. Mass.:
323.3856
SMILES:
COc1cc(\C=C/c2ccc3n(C)ccc3c2)cc(OC)c1OC
Structure:
Search PDB for entries with ligand similarity: