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Target
D(4) dopamine receptor
Ligand
BDBM50166021
Substrate
n/a
Meas. Tech.
ChEMBL_303360 (CHEMBL838695)
Ki
>25000±n/a nM
Citation
 Ding, K; Chen, J; Ji, M; Wu, X; Varady, J; Yang, CY; Lu, Y; Deschamps, JR; Levant, B; Wang, S Enantiomerically pure hexahydropyrazinoquinolines as potent and selective dopamine 3 subtype receptor ligands. J Med Chem 48:3171-81 (2005) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(4) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.4 | DRD4_RAT | Dopamine receptor | Drd4
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41307.65
Organism:
RAT
Description:
DOPAMINE D4.4 0 RAT::P30729
Residue:
387
Sequence:
MGNSSATGDGGLLAGRGPESLGTGTGLGGAGAAALVGGVLLIGMVLAGNSLVCVSVASERILQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGGVWLLSPRLCDTLMAMDVMLCTASIFNLCAISVDRFVAVTVPLRYNQQGQCQLLLIAATWLLSAAVAAPVVCGLNDVPGRDPTVCCLEDRDYVVYSSICSFFLPCPLMLLLYWATFRGLRRWEAARHTKLHSRAPRRPSGPGPPVSDPTQGPLFSDCPPPSPSLRTSPTVSSRPESDLSQSPCSPGCLLPDAALAQPPAPSSRRKRGAKITGRERKAMRVLPVVVGAFLMCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVNSALNPIIYTIFNAEFRSVFRKTLRLRC
  
Inhibitor
Name:
BDBM50166021
Synonyms:
CHEMBL193300 | Naphthalene-2-carboxylic acid {1-[2-((S)-8-methoxy-1,2,4,4a,5,6-hexahydro-pyrazino[1,2-a]quinolin-3-yl)-ethyl]-piperidin-4-yl}-amide
Type:
Small organic molecule
Emp. Form.:
C31H38N4O2
Mol. Mass.:
498.659
SMILES:
COc1ccc2N3CCN(CCN4CCC(CC4)NC(=O)c4ccc5ccccc5c4)C[C@@H]3CCc2c1
Structure:
Search PDB for entries with ligand similarity: