Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50170341
Substrate
n/a
Meas. Tech.
ChEMBL_302852 (CHEMBL828768)
Ki
124±n/a nM
Citation
 Huffman, JW; Szklennik, PV; Almond, A; Bushell, K; Selley, DE; He, H; Cassidy, MP; Wiley, JL; Martin, BR 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles. Bioorg Med Chem Lett 15:4110-3 (2005) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52856.55
Organism:
Rattus norvegicus (rat)
Description:
P20272
Residue:
473
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50170341
Synonyms:
1-(2-Methyl-1-pentyl-1H-indol-3-yl)-2-phenyl-ethanone | 1-(2-methyl-1-pentyl-1H-indol-3-yl)-2-phenylethanone | CHEMBL186525 | JWH-205
Type:
Small organic molecule
Emp. Form.:
C22H25NO
Mol. Mass.:
319.44
SMILES:
CCCCCn1c(C)c(C(=O)Cc2ccccc2)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: