Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50170941
Substrate
n/a
Meas. Tech.
ChEMBL_303601 (CHEMBL829690)
Ki
9±n/a nM
Citation
 Baraldi, PG; Tabrizi, MA; Preti, D; Bovero, A; Fruttarolo, F; Romagnoli, R; Zaid, NA; Moorman, AR; Varani, K; Borea, PA New 2-arylpyrazolo[4,3-c]quinoline derivatives as potent and selective human A3 adenosine receptor antagonists. J Med Chem 48:5001-8 (2005) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50170941
Synonyms:
2-p-Tolyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one | CHEMBL188035
Type:
Small organic molecule
Emp. Form.:
C17H13N3O
Mol. Mass.:
275.3046
SMILES:
Cc1ccc(cc1)-n1cc2c(n1)c1ccccc1[nH]c2=O
Structure:
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