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Target
D(2) dopamine receptor
Ligand
BDBM50171885
Substrate
n/a
Meas. Tech.
ChEMBL_303800 (CHEMBL829849)
Ki
670±n/a nM
Citation
 Fiorino, F; Perissutti, E; Severino, B; Santagada, V; Cirillo, D; Terracciano, S; Massarelli, P; Bruni, G; Collavoli, E; Renner, C; Caliendo, G New 5-hydroxytryptamine(1A) receptor ligands containing a norbornene nucleus: synthesis and in vitro pharmacological evaluation. J Med Chem 48:5495-503 (2005) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50171885
Synonyms:
4-{3-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]-propoxy}-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione | CHEMBL191226
Type:
Small organic molecule
Emp. Form.:
C23H26F3N3O3
Mol. Mass.:
449.466
SMILES:
FC(F)(F)c1cccc(c1)N1CCN(CCCON2C(=O)C3C4CC(C=C4)C3C2=O)CC1 |c:26|
Structure:
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