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Target
Mu-type opioid receptor
Ligand
BDBM50175738
Substrate
n/a
Meas. Tech.
ChEMBL_328877 (CHEMBL859856)
Ki
>4652±n/a nM
Citation
 Trabanco, AA; Pullan, S; Alonso, JM; Alvarez, RM; Andrés, JI; Boeckx, I; Fernández, J; Gómez, A; Iturrino, L; Janssens, FE; Leenaerts, JE; De Lucas, AI; Matesanz, E; Meert, T; Steckler, T 4-Phenyl-4-[1H-imidazol-2-yl]-piperidine derivatives, a novel class of selective delta-opioid agonists. Bioorg Med Chem Lett 16:146-9 (2005) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50175738
Synonyms:
4-(1-benzyl-1H-imidazol-2-yl)-N-(3-fluorophenyl)-4-phenylpiperidine-1-carboxamide | CHEMBL199647
Type:
Small organic molecule
Emp. Form.:
C28H27FN4O
Mol. Mass.:
454.5386
SMILES:
Fc1cccc(NC(=O)N2CCC(CC2)(c2nccn2Cc2ccccc2)c2ccccc2)c1
Structure:
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