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TargetCoagulation factor X
LigandBDBM50176257
Substrate/Competitorn/a
Meas. Tech.ChEMBL_334349
Ki 2±n/a nM
Citation Young, WBSprengeler, PShrader, WDLi, YRai, RVerner, EJenkins, TFatheree, PKolesnikov, AJanc, JWCregar, LElrod, KKatz, B Generation of potent coagulation protease inhibitors utilizing zinc-mediated chelation. Bioorg Med Chem Lett16:710-3 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Coagulation factor X
Name:Thrombin and coagulation factor X
Synonyms:Activated coagulation factor X (FXa) | Activated factor Xa heavy chain | Coagulation factor X precursor | Coagulation factor Xa | F10 | Factor X heavy chain | Factor X light chain | Factor Xa | Stuart factor | Stuart-Prower factor
Type:Enzyme
Mol. Mass.:54726.60
Organism:Homo sapiens (Human)
Description:n/a
Residue:488
Sequence:
MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEE
TCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKN
CELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERR
KRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQE
CKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGE
AVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGI
VSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSG
GPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPE
VITSSPLK
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  Blast E-value cutoff:
BDBM50176257
NameBDBM50176257
Synonyms:2-((5,6-dimethyl-1H-benzo[d]imidazol-2-yl)methyl)-1H-benzo[d]imidazole-5-carboxamidine | CHEMBL204589
TypeSmall organic molecule
Emp. Form.C18H18N6
Mol. Mass.318.3757
SMILESCc1cc2nc(Cc3nc4ccc(cc4[nH]3)C(N)=N)[nH]c2cc1C
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a