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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50178823
Substrate
n/a
Meas. Tech.
ChEMBL_326376 (CHEMBL867569)
Ki
63±n/a nM
Citation
 Ekegren, JK; Unge, T; Safa, MZ; Wallberg, H; Samuelsson, B; Hallberg, A A new class of HIV-1 protease inhibitors containing a tertiary alcohol in the transition-state mimicking scaffold. J Med Chem 48:8098-102 (2005) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50178823
Synonyms:
(2S)-2-Benzyl-3-[N-benzyl-N'-((2S)-2-methanesulfonylamino-3,3-dimethyl-butyryl)-hydrazino]-2-hydroxy-N-((1S,2R)-2-hydroxy-indan-1-yl)-propionamide | CHEMBL369929
Type:
Small organic molecule
Emp. Form.:
C33H42N4O6S
Mol. Mass.:
622.775
SMILES:
CC(C)(C)[C@H](NS(C)(=O)=O)C(=O)NN(Cc1ccccc1)C[C@@](O)(Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12
Structure:
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