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Target
Dual specificity protein phosphatase 3
Ligand
BDBM50179013
Substrate
n/a
Meas. Tech.
ChEMBL_339771 (CHEMBL862182)
IC50
>80000±n/a nM
Citation
 Cui, L; Na, M; Oh, H; Bae, EY; Jeong, DG; Ryu, SE; Kim, S; Kim, BY; Oh, WK; Ahn, JS Protein tyrosine phosphatase 1B inhibitors from Morus root bark. Bioorg Med Chem Lett 16:1426-9 (2006) [PubMed]  Article 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM50179013
Synonyms:
CHEMBL205924 | moracin O
Type:
Small organic molecule
Emp. Form.:
C19H18O5
Mol. Mass.:
326.3432
SMILES:
CC(C)(O)C1Cc2cc3cc(oc3cc2O1)-c1cc(O)cc(O)c1
Structure:
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