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Target
Matrilysin
Ligand
BDBM50180016
Substrate
n/a
Meas. Tech.
ChEMBL_329829 (CHEMBL862792)
IC50
>1000±n/a nM
Citation
 Pirard, B; Matter, H Matrix metalloproteinase target family landscape: a chemometrical approach to ligand selectivity based on protein binding site analysis. J Med Chem 49:51-69 (2006) [PubMed]  Article 
Target
Name:
Matrilysin
Synonyms:
MMP7 | MMP7_HUMAN | MPSL1 | Matrix metalloproteinase 7 | Matrix metalloproteinase-7 (MMP-7) | Matrix metalloproteinase-7 (MMP7) | PUMP1
Type:
Enzyme
Mol. Mass.:
29681.54
Organism:
Homo sapiens (Human)
Description:
P09237
Residue:
267
Sequence:
MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK
  
Inhibitor
Name:
BDBM50180016
Synonyms:
(S)-2-((4-(4-bromobenzamido)phenylsulfonyl)methyl)-3-(1H-indol-3-yl)propanoic acid | CHEMBL199917
Type:
Small organic molecule
Emp. Form.:
C25H21BrN2O5S
Mol. Mass.:
541.414
SMILES:
OC(=O)[C@H](Cc1c[nH]c2ccccc12)CS(=O)(=O)c1ccc(NC(=O)c2ccc(Br)cc2)cc1
Structure:
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