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Target
D(2) dopamine receptor
Ligand
BDBM50185778
Substrate
n/a
Meas. Tech.
ChEMBL_361716 (CHEMBL861448)
Ki
>1000±n/a nM
Citation
 Ladduwahetty, T; Boase, AL; Mitchinson, A; Quin, C; Patel, S; Chapman, K; MacLeod, AM A new class of selective, non-basic 5-HT2A receptor antagonists. Bioorg Med Chem Lett 16:3201-4 (2006) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50185778
Synonyms:
8-(2-(4-(2,4-difluorophenethyl)piperidin-1-ylsulfonyl)phenyl)quinoline | CHEMBL380682
Type:
Small organic molecule
Emp. Form.:
C28H26F2N2O2S
Mol. Mass.:
492.58
SMILES:
Fc1ccc(CCC2CCN(CC2)S(=O)(=O)c2ccccc2-c2cccc3cccnc23)c(F)c1
Structure:
Search PDB for entries with ligand similarity: