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TargetAdenosine receptor A3
LigandBDBM50190436
Substrate/Competitorn/a
Meas. Tech.ChEMBL_375257
Ki 180±n/a nM
Citation Tafi, ABernardini, CBotta, MCorelli, FAndreini, MMartinelli, AOrtore, GBaraldi, PGFruttarolo, FBorea, PATuccinardi, T Pharmacophore based receptor modeling: the case of adenosine A3 receptor antagonists. An approach to the optimization of protein models. J Med Chem49:4085-97 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adenosine receptor A3
Name:Adenosine receptor
Synonyms:A3 adenosine receptor (hA3) | Adenosine A3 receptor (A3AR)
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:36197.32
Organism:Homo sapiens (Human)
Description:P0DMS8
Residue:318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50190436
NameBDBM50190436
Synonyms:4-Ethyl-2-methyl-6-phenyl-pyridine-3,5-dicarboxylic acid diethyl ester | CHEMBL111260 | diethyl 4-ethyl-2-methyl-6-phenylpyridine-3,5-dicarboxylate
TypeSmall organic molecule
Emp. Form.C20H23NO4
Mol. Mass.341.4009
SMILESCCOC(=O)c1c(C)nc(-c2ccccc2)c(C(=O)OCC)c1CC
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
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