Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50192596
Substrate
n/a
Meas. Tech.
ChEMBL_422303 (CHEMBL907004)
Ki
18±n/a nM
Citation
 Huffman, JW; Padgett, LW; Isherwood, ML; Wiley, JL; Martin, BR 1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: new high affinity ligands for the cannabinoid CB1 and CB2 receptors. Bioorg Med Chem Lett 16:5432-5 (2006) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50192596
Synonyms:
CHEMBL385653 | JWH-244 | naphthalen-1-yl(1-pentyl-5-p-tolyl-1H-pyrrol-3-yl)methanone
Type:
Small organic molecule
Emp. Form.:
C27H27NO
Mol. Mass.:
381.5094
SMILES:
CCCCCn1cc(cc1-c1ccc(C)cc1)C(=O)c1cccc2ccccc12
Structure:
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