Reaction Details Report a problem with these data
Target
Sterol O-acyltransferase 2
Ligand
BDBM50147178
Substrate
n/a
Meas. Tech.
ChEMBL_424061 (CHEMBL855070)
IC50
170±n/a nM
Citation
 Park, KH; Park, YD; Han, JM; Im, KR; Lee, BW; Jeong, IY; Jeong, TS; Lee, WS Anti-atherosclerotic and anti-inflammatory activities of catecholic xanthones and flavonoids isolated from Cudrania tricuspidata. Bioorg Med Chem Lett 16:5580-3 (2006) [PubMed]  Article 
Target
Name:
Sterol O-acyltransferase 2
Synonyms:
ACACT2 | ACAT-2 | ACAT2 | Acetyl-CoA acetyltransferase, cytosolic | Acetyl-CoA transferase-like protein | Acyl coenzyme A:cholesterol acyltransferase 2 | Cholesterol acyltransferase 2 | Cytosolic acetoacetyl-CoA thiolase | SOAT2 | SOAT2_HUMAN
Type:
Enzyme
Mol. Mass.:
59912.75
Organism:
Homo sapiens (Human)
Description:
O75908
Residue:
522
Sequence:
MEPGGARLRLQRTEGLGGERERQPCGDGNTETHRAPDLVQWTRHMEAVKAQLLEQAQGQLRELLDRAMREAIQSYPSQDKPLPPPPPGSLSRTQEPSLGKQKVFIIRKSLLDELMEVQHFRTIYHMFIAGLCVFIISTLAIDFIDEGRLLLEFDLLIFSFGQLPLALVTWVPMFLSTLLAPYQALRLWARGTWTQATGLGCALLAAHAVVLCALPVHVAVEHQLPPASRCVLVFEQVRFLMKSYSFLREAVPGTLRARRGEGIQAPSFSSYLYFLFCPTLIYRETYPRTPYVRWNYVAKNFAQALGCVLYACFILGRLCVPVFANMSREPFSTRALVLSILHATLPGIFMLLLIFFAFLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLRLLGARARGVAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLVIGGMLNFMMHDQRTGPAWNVLMWTMLFLGQGIQVSLYCQEWYARRHCPLPQATFWGLVTPRSWSCHT
  
Inhibitor
Name:
BDBM50147178
Synonyms:
(Z)-Octadec-9-enoic acid phenylamide | CHEMBL15611 | oleic acid anilide
Type:
Small organic molecule
Emp. Form.:
C24H39NO
Mol. Mass.:
357.5726
SMILES:
CCCCCCCC\C=C/CCCCCCCC(=O)Nc1ccccc1
Structure:
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