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Target
Cathepsin S
Ligand
BDBM50247192
Substrate
n/a
Meas. Tech.
ChEMBL_518576 (CHEMBL959580)
Ki
5.5±n/a nM
Citation
 Li, J; Petrassi, HM; Tumanut, C; Masick, BT; Trussell, C; Harris, JL Substrate optimization for monitoring cathepsin C activity in live cells. Bioorg Med Chem 17:1064-70 (2009) [PubMed]  Article 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM50247192
Synonyms:
(S)-2-amino-N-((S)-5-phenyl-1-(phenylsulfonyl)pent-1-en-3-yl)pentanamide | CHEMBL514348
Type:
Small organic molecule
Emp. Form.:
C22H28N2O3S
Mol. Mass.:
400.534
SMILES:
CCC[C@H](N)C(=O)N[C@@H](CCc1ccccc1)\C=C\S(=O)(=O)c1ccccc1 |r|
Structure:
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