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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM81982
Substrate
n/a
Meas. Tech.
ChEMBL_541388 (CHEMBL1023943)
Ki
180±n/a nM
Citation
 Zampieri, D; Grazia Mamolo, M; Laurini, E; Zanette, C; Florio, C; Collina, S; Rossi, D; Azzolina, O; Vio, L Substituted benzo[d]oxazol-2(3H)-one derivatives with preference for the sigma1 binding site. Eur J Med Chem 44:124-30 (2008) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25266.54
Organism:
RAT
Description:
Q9R0C9
Residue:
223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM81982
Synonyms:
CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylguanidine | Tol2Gdn | cid_7333
Type:
Small organic molecule
Emp. Form.:
C15H17N3
Mol. Mass.:
239.3156
SMILES:
Cc1ccccc1NC(N)=Nc1ccccc1C |w:10.11|
Structure:
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