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Target
Glutathione transferase
Ligand
BDBM50227631
Substrate
n/a
Meas. Tech.
ChEMBL_553571 (CHEMBL958754)
IC50
0.900000±n/a nM
Citation
 Friesen, RW; Mancini, JA Microsomal prostaglandin E2 synthase-1 (mPGES-1): a novel anti-inflammatory therapeutic target. J Med Chem 51:4059-67 (2008) [PubMed]  Article 
Target
Name:
Glutathione transferase
Synonyms:
Microsomal prostaglandin E synthase-1
Type:
PROTEIN
Mol. Mass.:
17345.98
Organism:
Sus scrofa
Description:
ChEMBL_553571
Residue:
153
Sequence:
MPPPSLEMVSGQVLPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDAQRHGGLQYCRSDPDVERCLRAHRNDMETIYPFLFLGLVYSFLGPDPFVAWMHFLIFFLGRMVHTIAYLGKLRAPTRSLAYTLAQLPCASMALQIVWEAARHL
  
Inhibitor
Name:
BDBM50227631
Synonyms:
2-(6-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)isophthalonitrile | CHEMBL412099
Type:
Small organic molecule
Emp. Form.:
C23H11ClN4
Mol. Mass.:
378.813
SMILES:
Clc1ccc2c3[nH]c(nc3c3ccccc3c2c1)-c1c(cccc1C#N)C#N
Structure:
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