Reaction Details Report a problem with these data
Target
Lysophosphatidic acid receptor 2
Ligand
BDBM50271764
Substrate
n/a
Meas. Tech.
ChEMBL_556426 (CHEMBL955643)
IC50
28.3±n/a nM
Citation
 Fells, JI; Tsukahara, R; Fujiwara, Y; Liu, J; Perygin, DH; Osborne, DA; Tigyi, G; Parrill, AL Identification of non-lipid LPA3 antagonists by virtual screening. Bioorg Med Chem 16:6207-17 (2008) [PubMed]  Article 
Target
Name:
Lysophosphatidic acid receptor 2
Synonyms:
EDG4 | LPA receptor 2 | LPA-2 | LPA2 | LPAR2 | LPAR2_HUMAN | Lysophosphatidic acid receptor 2 | Lysophosphatidic acid receptor Edg-4
Type:
PROTEIN
Mol. Mass.:
39103.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1451385
Residue:
351
Sequence:
MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL
  
Inhibitor
Name:
BDBM50271764
Synonyms:
3-[4'-(3-Carboxy-acryloylamino)-biphenyl-4-ylcarbamoyl]-acrylic acid | CHEMBL482497
Type:
Small organic molecule
Emp. Form.:
C20H16N2O6
Mol. Mass.:
380.3508
SMILES:
OC(=O)\C=C\C(=O)Nc1ccc(cc1)-c1ccc(NC(=O)\C=C\C(O)=O)cc1
Structure:
Search PDB for entries with ligand similarity: