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TargetD(3) dopamine receptor
LigandBDBM50007522
Substrate/Competitorn/a
Meas. Tech.ChEMBL_491100
Ki 0.22±n/a nM
Citation Airaksinen, AJNag, SFinnema, SJMukherjee, JChattopadhyay, SGulyás, BFarde, LHalldin, C [11C]cyclopropyl-FLB 457: a PET radioligand for low densities of dopamine D2 receptors. Bioorg Med Chem16:6467-73 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
D(3) dopamine receptor
Name:D(3) dopamine receptor
Synonyms:D2-like dopamine receptor | DOPAMINE D3 | DRD3 | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:n/a
Mol. Mass.:44243.43
Organism:Homo sapiens (Human)
Description:n/a
Residue:400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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  Blast E-value cutoff:
BDBM50007522
NameBDBM50007522
Synonyms:5-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,3-dimethoxy-benzamide | 5-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2,3-dimethoxybenzamide | CHEMBL289330
TypeSmall organic molecule
Emp. Form.C16H23BrN2O3
Mol. Mass.371.269
SMILESCCN1CCC[C@H]1CNC(=O)c1cc(Br)cc(OC)c1OC |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a