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TargetAdenosine kinase
LigandBDBM50251863
Substrate/Competitorn/a
Meas. Tech.ChEMBL_491790
Ki 22000±n/a nM
Citation Kim, YASharon, AChu, CKRais, RHAl Safarjalani, ONNaguib, FNel Kouni, MH Structure-activity relationships of 7-deaza-6-benzylthioinosine analogues as ligands of Toxoplasma gondii adenosine kinase. J Med Chem51:3934-45 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adenosine kinase
Name:Adenosine kinase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:38353.04
Organism:Toxoplasma gondii
Description:ChEMBL_629062
Residue:363
Sequence:
MAVDSSNSATGPMRVFAIGNPILDLVAEVPSSFLDEFFLKRGDATLATPEQMRIYSTLDQ
FNPTSLPGGSALNSVRVVQKLLRKPGSAGYMGAIGDDPRGQVLKELCDKEGLATRFMVAP
GQSTGVCAVLINEKERTLCTHLGACGSFRLPEDWTTFASGALIFYATAYTLTATPKNALE
VAGYAHGIPNAIFTLNLSAPFCVELYKDAMQSLLLHTNILFGNEEEFAHLAKVHNLVAAE
KTALSTANKEHAVEVCTGALRLLTAGQNTGATKLVVMTRGHNPVIAAEQTADGTVVVHEV
GVPVVAAEKIVDTNGAGDAFVGGFLYALSQGKTVKQCIMCGNACAQDVIQHVGFSLSFTS
LPC
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  Blast E-value cutoff:
BDBM50251863
NameBDBM50251863
Synonyms:4-[(3-Trifluoromethylbenzyl)thio]-7-(beta-D-ribofuranosyl)-7Hpyrrolo[2,3-d]pyrimidine | CHEMBL481314
TypeSmall organic molecule
Emp. Form.C19H18F3N3O4S
Mol. Mass.441.424
SMILESOC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc2c(SCc3cccc(c3)C(F)(F)F)ncnc12 |r|
Structure
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n/a