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TargetBeta-2 adrenergic receptor and beta-3 adrenergic receptor
LigandBDBM50027663
Substrate/Competitorn/a
Meas. Tech.ChEMBL_537445
Ki 0.114000±n/a nM
Citation Sabio, MJones, KTopiol, S Use of the X-ray structure of the beta2-adrenergic receptor for drug discovery. Part 2: Identification of active compounds. Bioorg Med Chem Lett18:5391-5 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Beta-2 adrenergic receptor and beta-3 adrenergic receptor
Name:Beta-2 adrenergic receptor and beta-3 adrenergic receptor
Synonyms:ADRB2 | ADRB2R | B2AR | Beta-2 adrenergic receptor | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:n/a
Mol. Mass.:46461.69
Organism:Homo sapiens (Human)
Description:P07550
Residue:413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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  Blast E-value cutoff:
BDBM50027663
NameBDBM50027663
Synonyms:1-(9H-Carbazol-4-yloxy)-3-isopropylamino-propan-2-ol | 1-(9H-Carbazol-4-yloxy)-3-isopropylamino-propan-2-ol(carazolol) | 1-(9H-carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol | CHEMBL324665 | Carazolol | corazolol
TypeSmall organic molecule
Emp. Form.C18H22N2O2
Mol. Mass.298.3795
SMILESCC(C)NCC(O)COc1cccc2[nH]c3ccccc3c12
Structure
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n/a