Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50413165
Substrate
n/a
Meas. Tech.
ChEMBL_492975 (CHEMBL949441)
EC50
107.15±n/a nM
Citation
Christiansen, E; Urban, C; Merten, N; Liebscher, K; Karlsen, KK; Hamacher, A; Spinrath, A; Bond, AD; Drewke, C; Ullrich, S; Kassack, MU; Kostenis, E; Ulven, T Discovery of potent and selective agonists for the free fatty acid receptor 1 (FFA(1)/GPR40), a potential target for the treatment of type II diabetes. J Med Chem 51:7061-4 (2009) [PubMed] Article
More Info.:
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK