| Reaction Details |
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 | Report a problem with these data |
| Target | Lactoperoxidase |
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| Ligand | BDBM50241361 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_493330 |
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| IC50 | 11800±n/a nM |
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| Citation |  Das, D; Roy, G; Mugesh, G Antithyroid drug carbimazole and its analogues: synthesis and inhibition of peroxidase-catalyzed iodination of L-tyrosine. J Med Chem51:7313-7 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lactoperoxidase |
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| Name: | Lactoperoxidase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 80305.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_493330 |
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| Residue: | 712 |
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| Sequence: | MRVLLHLPALLASLILLQAAASTTRAQTTRTSAISDTVSQAKVQVNKAFLDSRTRLKTAM
SSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQKASLTNVTDPSLDLTSLSLE
VGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTP
GKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSE
YSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSLAREQINAL
TSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTT
ARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAF
VQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDE
NYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQ
PTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGL
YGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDS
LQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPWASVKN
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| BDBM50241361 |
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| Name | BDBM50241361 |
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| Synonyms: | CHEMBL1515 | METHIMAZOLE | US9138393, Methimazole | US9144538, Methimazole |
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| Type | Small organic molecule |
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| Emp. Form. | C4H6N2S |
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| Mol. Mass. | 114.169 |
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| SMILES | Cn1cc[nH]c1=S |
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| Structure |  |
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| n/a |
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