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Target
Lactoperoxidase
Ligand
BDBM50275893
Substrate
n/a
Meas. Tech.
ChEMBL_493330 (CHEMBL952393)
IC50
20500±n/a nM
Citation
 Das, D; Roy, G; Mugesh, G Antithyroid drug carbimazole and its analogues: synthesis and inhibition of peroxidase-catalyzed iodination of L-tyrosine. J Med Chem 51:7313-7 (2009) [PubMed]  Article 
Target
Name:
Lactoperoxidase
Synonyms:
LPO | PERL_HUMAN | SAPX
Type:
PROTEIN
Mol. Mass.:
80305.60
Organism:
Homo sapiens (Human)
Description:
ChEMBL_493330
Residue:
712
Sequence:
MRVLLHLPALLASLILLQAAASTTRAQTTRTSAISDTVSQAKVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQKASLTNVTDPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPWASVKN
  
Inhibitor
Name:
BDBM50275893
Synonyms:
CHEMBL469529 | ethyl 3-ethyl-2-thioxo-2,3-dihydro-1H-imidazole-1-carboxylate
Type:
Small organic molecule
Emp. Form.:
C8H12N2O2S
Mol. Mass.:
200.258
SMILES:
CCOC(=O)n1ccn(CC)c1=S
Structure:
Search PDB for entries with ligand similarity: