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Target
Beta-1 adrenergic receptor
Ligand
BDBM50255801
Substrate
n/a
Meas. Tech.
ChEMBL_516105 (CHEMBL983249)
Ki
7700±n/a nM
Citation
 Marona, H; Szkaradek, N; Rapacz, A; Filipek, B; Dybala, M; Siwek, A; Cegla, M; Szneler, E Preliminary evaluation of pharmacological properties of some xanthone derivatives. Bioorg Med Chem 17:1345-52 (2009) [PubMed]  Article 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
ADRB1R, B1AR | ADRB1_RAT | Adrb1 | Adrb1r | Adrenergic receptor beta | Beta-1 adrenoceptor | Beta-1 adrenoreceptor | adrenergic Beta1 | adrenergic Beta1,2
Type:
Protein
Mol. Mass.:
50486.84
Organism:
Rattus norvegicus (Rat)
Description:
P18090
Residue:
466
Sequence:
MGAGALALGASEPCNLSSAAPLPDGAATAARLLVLASPPASLLPPASEGSAPLSQQWTAGMGLLLALIVLLIVVGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITLPFRYQSLLTRARARALVCTVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLTGPPRPPSPAPSPSPGPPRPADSLANGRSSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAACRRRAAHGDRPRASGCLARAGPPPSPGAPSDDDDDDAGATPPARLLEPWAGCNGGTTTVDSDSSLDEPGRQGFSSESKV
  
Inhibitor
Name:
BDBM50255801
Synonyms:
4-(3-(Allylamino)propoxy)-9H-xanthen-9-one hydrochloride | CHEMBL517532
Type:
Small organic molecule
Emp. Form.:
C19H19NO3
Mol. Mass.:
309.3591
SMILES:
C=CCNCCCOc1cccc2c1oc1ccccc1c2=O
Structure:
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