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Target
Cholecystokinin receptor type A
Ligand
BDBM50185262
Substrate
n/a
Meas. Tech.
ChEMBL_564593 (CHEMBL964033)
IC50
197±n/a nM
Citation
 Lassiani, L; Pavan, MV; Berti, F; Kokotos, G; Markidis, T; Mennuni, L; Makovec, F; Varnavas, A Anthranilic acid based CCK1 receptor antagonists: blocking the receptor with the same 'words' of the endogenous ligand. Bioorg Med Chem 17:2336-50 (2009) [PubMed]  Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49676.37
Organism:
RAT
Description:
Cholecystokinin central 0 RAT::P30551
Residue:
444
Sequence:
MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRALLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50185262
Synonyms:
(+/-)-2-(2-(1H-indole-2-carboxamido)benzamido)-3-phenylpropanoic acid | 2(R,S)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}-3-phenylpropionic acid | 2-(2-(1H-indole-2-carboxamido)benzamido)-3-phenylpropanoic acid | CHEMBL202861
Type:
Small organic molecule
Emp. Form.:
C25H21N3O4
Mol. Mass.:
427.4519
SMILES:
OC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1
Structure:
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