Reaction Details Report a problem with these data
Target
Cholecystokinin receptor type A
Ligand
BDBM50278816
Substrate
n/a
Meas. Tech.
ChEMBL_564593 (CHEMBL964033)
IC50
288±n/a nM
Citation
 Lassiani, L; Pavan, MV; Berti, F; Kokotos, G; Markidis, T; Mennuni, L; Makovec, F; Varnavas, A Anthranilic acid based CCK1 receptor antagonists: blocking the receptor with the same 'words' of the endogenous ligand. Bioorg Med Chem 17:2336-50 (2009) [PubMed]  Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49676.37
Organism:
RAT
Description:
Cholecystokinin central 0 RAT::P30551
Residue:
444
Sequence:
MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRALLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50278816
Synonyms:
2-(R,S)-{2-[(1H-Indole-2-carbonyl)-amino]-benzoylamino}-3-methyl-butyric acid | CHEMBL496066
Type:
Small organic molecule
Emp. Form.:
C21H21N3O4
Mol. Mass.:
379.4091
SMILES:
CC(C)C(NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1)C(O)=O
Structure:
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