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Target
Prostaglandin D2 receptor
Ligand
BDBM50277941
Substrate
n/a
Meas. Tech.
ChEMBL_501282 (CHEMBL971468)
Ki
4±n/a nM
Citation
 Leblanc, Y; Roy, P; Dufresne, C; Lachance, N; Wang, Z; O'Neill, G; Greig, G; Denis, D; Mathieu, MC; Slipetz, D; Sawyer, N; Tsou, N Discovery of potent and selective DP1 receptor antagonists in the azaindole series. Bioorg Med Chem Lett 19:2125-8 (2009) [PubMed]  Article 
Target
Name:
Prostaglandin D2 receptor
Synonyms:
PD2R_HUMAN | PTGDR | Prostaglandin D2 | Prostaglandin D2 receptor | Prostanoid DP receptor
Type:
Enzyme
Mol. Mass.:
40288.87
Organism:
Homo sapiens (Human)
Description:
Q13258
Residue:
359
Sequence:
MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
  
Inhibitor
Name:
BDBM50277941
Synonyms:
(+/-)-2-(5-(4-chlorophenylthio)-4-(methylsulfonyl)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-6-yl)acetic acid | CHEMBL484525
Type:
Small organic molecule
Emp. Form.:
C20H19ClN2O4S2
Mol. Mass.:
450.959
SMILES:
CS(=O)(=O)c1ccnc2n3CCCC(CC(O)=O)c3c(Sc3ccc(Cl)cc3)c12
Structure:
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