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Target
Leukotriene B4 receptor 1
Ligand
BDBM50280292
Substrate
n/a
Meas. Tech.
ChEMBL_99654 (CHEMBL709312)
IC50
2.9±n/a nM
Citation
 Sofia, MJ; SaussyJr., DL; Jackson, WT; Marder, P; Silbaugh, SA; Froelich, LL; Cockerham, SL; Stengel, PW Ortho-alkoxyphenol leukotriene B4 receptor antagonists: effect of a chroman carboxylic acid. Bioorg Med Chem Lett 2:1675-1680 (1992)    Article 
Target
Name:
Leukotriene B4 receptor 1
Synonyms:
BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37582.68
Organism:
Homo sapiens (Human)
Description:
Q15722
Residue:
352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
  
Inhibitor
Name:
BDBM50280292
Synonyms:
7-[3-(2-Ethyl-5-hydroxy-4-methoxy-phenoxy)-propoxy]-8-propyl-chroman-2-carboxylic acid | CHEMBL294987
Type:
Small organic molecule
Emp. Form.:
C25H32O7
Mol. Mass.:
444.5174
SMILES:
CCCc1c(OCCCOc2cc(O)c(OC)cc2CC)ccc2CCC(Oc12)C(O)=O
Structure:
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