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Target
Glucagon receptor
Ligand
BDBM50280717
Substrate
n/a
Meas. Tech.
ChEBML_219265
IC50
4000±n/a nM
Citation
 Collins, JL; Dambek, PJ; Goldstein, SW; Faraci, W CP-99,711: a non-peptide glucagon receptor antagonist Bioorg Med Chem Lett 2:915-918 (1992)    Article 
Target
Name:
Glucagon receptor
Synonyms:
GL-R | GLR_RAT | Gcgr
Type:
PROTEIN
Mol. Mass.:
55053.40
Organism:
Rattus norvegicus
Description:
ChEMBL_1450588
Residue:
485
Sequence:
MLLTQLHCPYLLLLLVVLSCLPKAPSAQVMDFLFEKWKLYSDQCHHNLSLLPPPTELVCNRTFDKYSCWPDTPPNTTANISCPWYLPWYHKVQHRLVFKRCGPDGQWVRGPRGQSWRDASQCQMDDDEIEVQKGVAKMYSSYQVMYTVGYSLSLGALLLALVILLGLRKLHCTRNYIHGNLFASFVLKAGSVLVIDWLLKTRYSQKIGDDLSVSVWLSDGAVAGCRVATVIMQYGIIANYCWLLVEGVYLYSLLSITTFSEKSFFSLYLCIGWGSPLLFVIPWVVVKCLFENVQCWTSNDNMGFWWILRIPVLLAILINFFIFVRIIHLLVAKLRAHQMHYADYKFRLARSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSTKLFFDLFFSSFQGLLVAVLYCFLNKEVQAELLRRWRRWQEGKALQEERMASSHGSHMAPAGTCHGDPCEKLQLMSAGSSSGTGCEPSAKTSLASSLPRLADSPT
  
Inhibitor
Name:
BDBM50280717
Synonyms:
CHEMBL557974 | CP-99711 | N-[6,7-Dichloro-3-((E)-styryl)-quinoxalin-2-yl]-N,N',N'-trimethyl-propane-1,3-diamine; hydrochloride
Type:
Small organic molecule
Emp. Form.:
C22H24Cl2N4
Mol. Mass.:
415.359
SMILES:
CN(C)CCCN(C)c1nc2cc(Cl)c(Cl)cc2nc1\C=C\c1ccccc1
Structure:
Search PDB for entries with ligand similarity: