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Target
5-hydroxytryptamine receptor 1D
Ligand
BDBM50285319
Substrate
n/a
Meas. Tech.
ChEMBL_1626 (CHEMBL616512)
IC50
1.98±n/a nM
Citation
 LeBoulluec, KL; Mattson, RJ; Mahle, CD; McGovern, RT; Nowak, HP; Gentile, AJ Bivalent indoles exhibiting serotonergic binding affinity Bioorg Med Chem Lett 5:123-126 (1995)    Article 
Target
Name:
5-hydroxytryptamine receptor 1D
Synonyms:
5-HT-1D | 5-HT-1D-alpha | 5-HT1D | 5-hydroxytryptamine receptor 1D (5-HT1D) | 5HT1D_HUMAN | HTR1D | HTR1DA | HTRL | Serotonin (5-HT) receptor | Serotonin Receptor 1D
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41920.63
Organism:
Homo sapiens (Human)
Description:
Receptor binding assays were performed using human clone stably expressed in CHO cells.
Residue:
377
Sequence:
MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVLTTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAKAQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKATKILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKIVPFRKAS
  
Inhibitor
Name:
BDBM50285319
Synonyms:
3-(4-Heptylamino-cyclohex-1-enyl)-1H-indole-5-carboxylic acid amide | CHEMBL417650
Type:
Small organic molecule
Emp. Form.:
C22H31N3O
Mol. Mass.:
353.501
SMILES:
CCCCCCCNC1CCC(=CC1)c1c[nH]c2ccc(cc12)C(N)=O |c:11|
Structure:
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