Reaction Details Report a problem with these data
Target
Cholecystokinin receptor type A
Ligand
BDBM50286895
Substrate
n/a
Meas. Tech.
ChEBML_50038
IC50
105±n/a nM
Citation
 Semple, G; Ryder, H; Kendrick, DA; Szelke, M; Ohta, M; Satoh, M; Nishida, A; Akuzawa, S; Miyata, K Synthesis and biological activity of 5-heteroaryl benzodiazepines: analogues of YM022 Bioorg Med Chem Lett 6:55-58 (1996)    Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49676.37
Organism:
RAT
Description:
Cholecystokinin central 0 RAT::P30551
Residue:
444
Sequence:
MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRALLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50286895
Synonyms:
1-(3,3-Dimethyl-2-oxo-butyl)-5-(1H-pyrazol-3-yl)-3-[(m-tolylamino-methyl)-amino]-1,3-dihydro-benzo[e][1,4]diazepin-2-one | CHEMBL345880
Type:
Small organic molecule
Emp. Form.:
C26H30N6O2
Mol. Mass.:
458.5554
SMILES:
Cc1cccc(NCNC2N=C(c3ccn[nH]3)c3ccccc3N(CC(=O)C(C)(C)C)C2=O)c1 |t:10|
Structure:
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