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TargetCholesteryl ester transfer protein
LigandBDBM50287675
Substrate/Competitorn/a
Meas. Tech.ChEBML_48940
IC50 6000±n/a nM
Citation Pietzonka, TDamon, RRussell, MWattanasin, S Phosphonate-containing analogs of cholesteryl ester as novel inhibitors of cholesteryl ester transfer protein Bioorg Med Chem Lett6:1951-1954 (1996)    Article
More Info.:Get all data from this article,  Assay Method
 
Cholesteryl ester transfer protein
Name:Cholesteryl ester transfer protein
Synonyms:CETP | Cholesteryl ester transfer protein (CETP) | Lipid transfer protein I
Type:Enzyme
Mol. Mass.:54751.53
Organism:Homo sapiens (Human)
Description:P11597
Residue:493
Sequence:
MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDI
TGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTT
AWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWI
KQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVI
TASYLESHHKGHFIYKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRL
MLSLMGDEFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSS
VMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSE
SVQSFLQSMITAVGIPEVMSRLEVVFTALMNSKGVSLFDIINPEIITRDGFLLLQMDFGF
PEHLLVDFLQSLS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50287675
NameBDBM50287675
Synonyms:CHEMBL58643 | Tetradecyl-phosphonic acid mono-(3-phenoxy-benzyl) ester
TypeSmall organic molecule
Emp. Form.C27H41O4P
Mol. Mass.460.5858
SMILESCCCCCCCCCCCCCCP(O)(=O)OCc1cccc(Oc2ccccc2)c1
Structure
n/a