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Target
Cholesteryl ester transfer protein
Ligand
BDBM50287675
Substrate
n/a
Meas. Tech.
ChEBML_48940
IC50
6000±n/a nM
Citation
 Pietzonka, T; Damon, R; Russell, M; Wattanasin, S Phosphonate-containing analogs of cholesteryl ester as novel inhibitors of cholesteryl ester transfer protein Bioorg Med Chem Lett 6:1951-1954 (1996)    Article 
Target
Name:
Cholesteryl ester transfer protein
Synonyms:
CETP | CETP_HUMAN | Cholesteryl ester transfer protein (CETP) | Lipid transfer protein I
Type:
Enzyme
Mol. Mass.:
54751.53
Organism:
Homo sapiens (Human)
Description:
P11597
Residue:
493
Sequence:
MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDITGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTTAWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWIKQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVITASYLESHHKGHFIYKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRLMLSLMGDEFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSSVMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSESVQSFLQSMITAVGIPEVMSRLEVVFTALMNSKGVSLFDIINPEIITRDGFLLLQMDFGFPEHLLVDFLQSLS
  
Inhibitor
Name:
BDBM50287675
Synonyms:
CHEMBL58643 | Tetradecyl-phosphonic acid mono-(3-phenoxy-benzyl) ester
Type:
Small organic molecule
Emp. Form.:
C27H41O4P
Mol. Mass.:
460.5858
SMILES:
CCCCCCCCCCCCCCP(O)(=O)OCc1cccc(Oc2ccccc2)c1
Structure:
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