Reaction Details Report a problem with these data
Target
Tissue alpha-L-fucosidase
Ligand
BDBM50288854
Substrate
n/a
Meas. Tech.
ChEBML_216813
IC50
>1000000±n/a nM
Citation
 Igarashi, Y; Ichikawa, M; Ichikawa, Y Synthesis of a new inhibitor of α-fucosidase Bioorg Med Chem Lett 6:553-558 (1996)    Article 
Target
Name:
Tissue alpha-L-fucosidase
Synonyms:
Alpha-L-fucosidase I | Alpha-L-fucoside fucohydrolase | FUCA1 | FUCO_HUMAN | Tissue alpha-L-fucosidase
Type:
PROTEIN
Mol. Mass.:
53690.69
Organism:
Homo sapiens (Human)
Description:
ChEMBL_34088
Residue:
466
Sequence:
MRAPGMRSRPAGPALLLLLLFLGAAESVRRAQPPRRYTPDWPSLDSRPLPAWFDEAKFGVFIHWGVFSVPAWGSEWFWWHWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEWADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYGLYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK
  
Inhibitor
Name:
BDBM50288854
Synonyms:
5-Methylene-piperidine-3,4-diol | CHEMBL150938
Type:
Small organic molecule
Emp. Form.:
C6H11NO2
Mol. Mass.:
129.157
SMILES:
OC1CNCC(=C)C1O
Structure:
Search PDB for entries with ligand similarity: