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Target
D(2) dopamine receptor
Ligand
BDBM50292471
Substrate
n/a
Meas. Tech.
ChEMBL_483726 (CHEMBL997481)
IC50
>100000±n/a nM
Citation
 Cortes, D; Figadere, B; Saez, J; Protais, P Displacement Activity of Bisbenzylisoquinoline Alkaloids at Striatal 3H-SCH 23390 and 3H-Raclopride Binding Sites J Nat Prod 55:1281-1286 (1992) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50292471
Synonyms:
CHEMBL449016 | CHEMBL504801 | Pampulhamine
Type:
Small organic molecule
Emp. Form.:
C38H44N2O6
Mol. Mass.:
624.7658
SMILES:
COc1ccc(C[C@H]2N(C)CCc3cc(OC)c(OC)cc23)cc1Oc1ccc(C[C@H]2NCCc3cc(OC)c(OC)cc23)cc1 |r|
Structure:
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