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Target
Delta-type opioid receptor
Ligand
BDBM50304076
Substrate
n/a
Meas. Tech.
ChEMBL_601677 (CHEMBL1049575)
IC50
121±n/a nM
Citation
 Peng, Y; Zhang, Q; Arora, S; Keenan, SM; Kortagere, S; Wannemacher, KM; Howells, RD; Welsh, WJ Novel delta opioid receptor agonists exhibit differential stimulation of signaling pathways. Bioorg Med Chem 17:6442-50 (2009) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40577.25
Organism:
MOUSE
Description:
P32300
Residue:
372
Sequence:
MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50304076
Synonyms:
3-(2-(4-tert-Butylphenyl)-5-((dimethylamino)methyl)-2H-1,2,4-triazol-3-yl)phenol | CHEMBL593613
Type:
Small organic molecule
Emp. Form.:
C21H26N4O
Mol. Mass.:
350.4573
SMILES:
CN(C)Cc1nc(-c2cccc(O)c2)n(n1)-c1ccc(cc1)C(C)(C)C
Structure:
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