Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50304630
Substrate
n/a
Meas. Tech.
ChEMBL_604437 (CHEMBL1070693)
Ki
1.04±n/a nM
Citation
 Choi, WJ; Lee, HW; Kim, HO; Chinn, M; Gao, ZG; Patel, A; Jacobson, KA; Moon, HR; Jung, YH; Jeong, LS Design and synthesis of N(6)-substituted-4'-thioadenosine-5'-uronamides as potent and selective human A(3) adenosine receptor agonists. Bioorg Med Chem 17:8003-11 (2009) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50304630
Synonyms:
9-(5'-Cyclobutylaminocarbonyl-4'-thio-beta-D-ribofuranosyl)-N6-methyladenine | CHEMBL606630
Type:
Small organic molecule
Emp. Form.:
C15H20N6O3S
Mol. Mass.:
364.423
SMILES:
CNc1ncnc2n(cnc12)[C@@H]1S[C@@H]([C@@H](O)[C@H]1O)C(=O)NC1CCC1 |r|
Structure:
Search PDB for entries with ligand similarity: