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Target
Papain
Ligand
BDBM50304796
Substrate
n/a
Meas. Tech.
ChEMBL_606254 (CHEMBL1069944)
Ki
6.3±n/a nM
Citation
 Löser, R; Gut, J; Rosenthal, PJ; Frizler, M; Gütschow, M; Andrews, KT Antimalarial activity of azadipeptide nitriles. Bioorg Med Chem Lett 20:252-5 (2010) [PubMed]  Article 
Target
Name:
Papain
Synonyms:
Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I
Type:
Enzyme
Mol. Mass.:
38923.01
Organism:
Carica papaya
Description:
Papain was purchased from Sigma, Germany.
Residue:
345
Sequence:
MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYKNIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTELSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNEYSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYGPNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
  
Inhibitor
Name:
BDBM50304796
Synonyms:
(S)-benzyl 1-(2-cyano-1-methyl-2-phenethylhydrazinyl)-1-oxo-3-phenylpropan-2-ylcarbamate | CHEMBL604079 | acs.jmedchem.1c00409_ST.402
Type:
Small organic molecule
Emp. Form.:
C27H28N4O3
Mol. Mass.:
456.5362
SMILES:
CN(N(CCc1ccccc1)C#N)C(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 |r|
Structure:
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