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TargetNeutral sphingomyelinase
LigandBDBM50308981
Substrate/Competitorn/a
Meas. Tech.ChEMBL_611790
IC50>100000±n/a nM
Citation Roth, AGRedmer, SArenz, C Development of carbohydrate-derived inhibitors of acid sphingomyelinase. Bioorg Med Chem18:939-44 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Neutral sphingomyelinase
Name:Neutral sphingomyelinase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:47651.22
Organism:Rattus norvegicus
Description:ChEMBL_611790
Residue:422
Sequence:
MKHNFSLRLRVFNLNCWDIPYLSKHRADRMKRLGDFLNLESFDLALLEEVWSEQDFQYLK
QKLSLTYPDAHYFRSGIIGSGLCVFSRHPIQEIVQHVYTLNGYPYKFYHGDWFCGKAVGL
LVLHLSGLVLNAYVTHLHAEYSRQKDIYFAHRVAQAWELAQFIHHTSKKANVVLLCGDLN
MHPKDLGCCLLKEWTGLRDAFVETEDFKGSEDGCTMVPKNCYVSQQDLGPFPFGVRIDYV
LYKAVSGFHICCKTLKTTTGCDPHNGTPFSDHEALMATLCVKHSPPQEDPCSAHGSAERS
ALISALREARTELGRGIAQARWWAALFGYVMILGLSLLVLLCVLAAGEEAREVAIMLWTP
SVGLVLGAGAVYLFHKQEAKSLCRAQAEIQHVLTRTTETQDLGSEPHPTHCRQQEADRAE
EK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50308981
NameBDBM50308981
Synonyms:6-O-Hexylsulfonyl-D-glucose-2,4-bisphosphate | CHEMBL600243
TypeSmall organic molecule
Emp. Form.C12H26O14P2S
Mol. Mass.488.339
SMILESCCCCCCS(=O)(=O)OC[C@H]1OC(O)[C@H](OP(O)(O)=O)[C@@H](O)[C@@H]1OP(O)(O)=O |r|
Structure
n/a