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Target
High affinity choline transporter 1
Ligand
BDBM50323515
Substrate
n/a
Meas. Tech.
ChEMBL_644788 (CHEMBL1211031)
Ki
10±n/a nM
Citation
 Geldenhuys, WJ; Allen, DD; Lockman, PR 3-D-QSAR and docking studies on the neuronal choline transporter. Bioorg Med Chem Lett 20:4870-7 (2010) [PubMed]  Article 
Target
Name:
High affinity choline transporter 1
Synonyms:
CHT | Cht1 | Hemicholinium-3-sensitive choline transporter | SC5A7_RAT | Slc5a7 | Solute carrier family 5 member 7
Type:
PROTEIN
Mol. Mass.:
63400.14
Organism:
Rattus norvegicus
Description:
ChEMBL_644788
Residue:
580
Sequence:
MPFHVEGLVAIILFYLLIFLVGIWAAWKTKNSGNAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYGPGCGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDVNISVIVSALIAILYTLVGGLYSVAYTDVVQLFCIFIGLWISVPFALSHPAVTDIGFTAVHAKYQSPWLGTIESVEVYTWLDNFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMALPAICIGAIGASTDWNQTAYGFPDPKTKEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIIIFPQLLCVLFIKGTNTYGAVAGYIFGLFLRITGGEPYLYLQPLIFYPGYYPDKNGIYNQRFPFKTLSMVTSFFTNICVSYLAKYLFESGTLPPKLDIFDAVVSRHSEENMDKTILVRNENIKLNELAPVKPRQSLTLSSTFTNKEALLDVDSSPEGSGTEDNLQ
  
Inhibitor
Name:
BDBM50323515
Synonyms:
CHEMBL1209714 | Hemicholinium
Type:
Small organic molecule
Emp. Form.:
C24H34N2O4
Mol. Mass.:
414.5367
SMILES:
C[N+]1(C)CCO[C@](O)(C1)c1ccc(cc1)-c1ccc(cc1)[C@@]1(O)C[N+](C)(C)CCO1 |r|
Structure:
Search PDB for entries with ligand similarity: