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Target
Oxytocin receptor
Ligand
BDBM50326718
Substrate
n/a
Meas. Tech.
ChEMBL_661577 (CHEMBL1253141)
Ki
90±n/a nM
Citation
 Borthwick, AD Oral oxytocin antagonists. J Med Chem 53:6525-38 (2010) [PubMed]  Article 
Target
Name:
Oxytocin receptor
Synonyms:
OT-R | OXTR | OXYR_HUMAN | Oxytocin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42793.26
Organism:
Homo sapiens (Human)
Description:
Oxytocin OXTR HEK293::B2R9L7
Residue:
389
Sequence:
MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREVADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGETSASKKSNSSSFVLSHRSSSQRSCSQPSTA
  
Inhibitor
Name:
BDBM50326718
Synonyms:
CHEMBL1254116 | N-(2-oxo-2-(2-(2-oxoindolin-3-ylidene)hydrazinyl)ethyl)-N-phenylbenzenesulfonamide
Type:
Small organic molecule
Emp. Form.:
C22H18N4O4S
Mol. Mass.:
434.468
SMILES:
O=C(CN(c1ccccc1)S(=O)(=O)c1ccccc1)NN=C1C(=O)Nc2ccccc12 |w:20.21|
Structure:
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