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Target
Arylamine N-acetyltransferase
Ligand
BDBM50336283
Substrate
n/a
Meas. Tech.
ChEMBL_716569 (CHEMBL1670293)
IC50
>50000±n/a nM
Citation
 Fullam, E; Abuhammad, A; Wilson, DL; Anderton, MC; Davies, SG; Russell, AJ; Sim, E Analysis ofß-amino alcohols as inhibitors of the potential anti-tubercular target N-acetyltransferase. Bioorg Med Chem Lett 21:1185-90 (2011) [PubMed]  Article 
Target
Name:
Arylamine N-acetyltransferase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
31199.77
Organism:
Pseudomonas aeruginosa
Description:
ChEMBL_716570
Residue:
279
Sequence:
MTPLTPEQTHAYLHHIGIDDPGPPSLANLDRLIDAHLRRVAFENLDVLLDRPIEIDADKVFAKVVEGSRGGYCFELNSLFARLLLALGYELELLVARVRWGLPDDAPLTQQSHLMLRLYLAEGEFLVDVGFGSANPPRALPLPGDEADAGQVHCVRLVDPHAGLYESAVRGRSGWLPLYRFDLRPQLWIDYIPRNWYTSTHPHSVFRQGLKAAITEGDLRLTLADGLFGQRAGNGETLQRQLRDVEELLDILQTRFRLRLDPASEVPALARRLAGLISA
  
Inhibitor
Name:
BDBM50336283
Synonyms:
3-[3'-(4-cyclopent-2'''-en-1'''-ylphenoxy)-2'-hydroxypropyl]-5,5-dimethylimidazolidine-2,4-dione | CHEMBL1669811
Type:
Small organic molecule
Emp. Form.:
C19H26N2O4
Mol. Mass.:
346.4207
SMILES:
CC1(C)NC(=O)N(CC(O)COc2ccc(cc2)C2CCCC2)C1=O
Structure:
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