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TargetKappa-type opioid receptor
LigandBDBM50336679
Substrate/Competitorn/a
Meas. Tech.ChEMBL_722916
Ki 0.116±n/a nM
Citation Nemoto, TYamamoto, NWatanabe, AFujii, HHasebe, KNakajima, MMochizuki, HNagase, H Synthesis of 6,14-epoxymorphinan derivatives and their pharmacologies. Bioorg Med Chem19:1205-21 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Kappa-type opioid receptor
Name:Kappa-type opioid receptor
Synonyms:Kappa Opioid Receptor | OPIATE Kappa | Opiate Kappa 1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:42744.99
Organism:Cavia porcellus (domestic guinea pig)
Description:P41144
Residue:380
Sequence:
MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRV
RNTVQDPAYMRNVDGVNKPV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50336679
NameBDBM50336679
Synonyms:CHEMBL1672486 | N-[(6beta,14beta-Epoxy-3-hydroxy-17-isobutylmorphinan-6alpha-yl)methyl]-3-hydroxybenzamide
TypeSmall organic molecule
Emp. Form.C28H34N2O4
Mol. Mass.462.5806
SMILESCC(C)CN1CC[C@]23C[C@]4(CNC(=O)c5cccc(O)c5)CC[C@@]2(O4)[C@H]1Cc1ccc(O)cc31 |r,THB:3:4:23:33.27.26|
Structure
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n/a