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Target
Mu-type opioid receptor
Ligand
BDBM50336662
Substrate
n/a
Meas. Tech.
ChEMBL_722917 (CHEMBL1674428)
Ki
0.188±n/a nM
Citation
 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Synthesis of 6,14-epoxymorphinan derivatives and their pharmacologies. Bioorg Med Chem 19:1205-21 (2011) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50336662
Synonyms:
CHEMBL1672474 | N-[(17-Cyclopropylmethyl-6beta,14beta-epoxy-3-hydroxymorphinan-6alpha-yl)methyl]-N-methylbenzamide
Type:
Small organic molecule
Emp. Form.:
C29H34N2O3
Mol. Mass.:
458.5919
SMILES:
CN(C[C@@]12CC[C@@]3(O1)[C@H]1Cc4ccc(O)cc4[C@]3(C2)CCN1CC1CC1)C(=O)c1ccccc1 |r,THB:22:21:6:16.10.9|
Structure:
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