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Target
Alpha-amylase
Ligand
BDBM50339930
Substrate
n/a
Meas. Tech.
ChEMBL_740884 (CHEMBL1763985)
Ki
110000±n/a nM
Citation
 Park, S; Hyun, S; Do, SI; Yu, J Selectivea-glucosidase substrates and inhibitors containing short aromatic peptidyl moieties. Bioorg Med Chem Lett 21:2441-4 (2011) [PubMed]  Article 
Target
Name:
Alpha-amylase
Synonyms:
Alpha-glucosidase
Type:
PROTEIN
Mol. Mass.:
65231.69
Organism:
Bacillus stearothermophilus
Description:
ChEMBL_740884
Residue:
555
Sequence:
MKKTWWKEGVAYQIYPRSFMDANGDGIGDLRGIIEKLDYLVELGVDIVWICPIYRSPNADNGYDISDYYAIMDEFGTMDDFDELLAQAHRRGLKIILDLVINHTSDEHPWFIESRSSRDNPKRDWYIWRDGKDGREPNNWESIFGGSAWQYDERTGQYYLHLFDVKQPDLNWENSEVRQALYDMINWWLDKGIDGFRIDAISHIKKKPGLPDLPNPKGLKYVPSFAAHMNQPGIMEYLRELKEQTFARYDIMTVGEANGVTVDEAEQWVGEENGVFHMIFQFEHLGLWKRKADGSIDVRRLKRTLTKWQKGLENRGWNALFLENHDLPRSVSTWGNDREYWAESAKALGALYFFMQGTPFIYQGQEIGMTNVQFSDIRDYRDVAALRLYELERANGRTHEEVMKIIWKTGRDNSRTPMQWSDAPNAGFTTGTPWIKVNENYRTINVEAERRDPNSVWSFYRQMIQLRKANELFVYGAYDLLLENHPSIYAYTRTLGRDRALIIVNVSDRPSLYRYDGFRLQSSDLALSNYPVRPHKNATRFKLKPYEARVYIWKE
  
Inhibitor
Name:
BDBM50339930
Synonyms:
CHEMBL1761668 | N1-((S)-1-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-N4-(4-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)phenyl)succinamide
Type:
Small organic molecule
Emp. Form.:
C36H41N5O11
Mol. Mass.:
719.7376
SMILES:
NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CCC(=O)Nc1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r|
Structure:
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