Reaction Details Report a problem with these data
Target
Vasopressin V2 receptor
Ligand
BDBM50350874
Substrate
n/a
Meas. Tech.
ChEMBL_763492 (CHEMBL1819841)
EC50
9.2±n/a nM
Citation
 Wisniewski, K; Galyean, R; Tariga, H; Alagarsamy, S; Croston, G; Heitzmann, J; Kohan, A; Wisniewska, H; Laporte, R; Rivière, PJ; Schteingart, CD New, potent, selective, and short-acting peptidic V1a receptor agonists. J Med Chem 54:4388-98 (2011) [PubMed]  Article 
Target
Name:
Vasopressin V2 receptor
Synonyms:
ADHR | AVPR V2 | AVPR2 | Antidiuretic hormone receptor | DIR | DIR3 | Renal-type arginine vasopressin receptor | V2R | V2R_HUMAN | VASOPRESSIN V2 | Vasopressin V2 receptor | Vasopressin receptor
Type:
Receptor
Mol. Mass.:
40295.28
Organism:
Homo sapiens (Human)
Description:
P30518
Residue:
371
Sequence:
MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARGRTPPSLGPQDESCTTASSSLAKDTSS
  
Inhibitor
Name:
BDBM50350874
Synonyms:
CHEMBL1819540
Type:
Small organic molecule
Emp. Form.:
C45H63N13O11S2
Mol. Mass.:
1026.192
SMILES:
NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)NCC(N)=O |r|
Structure:
Search PDB for entries with ligand similarity: